Chemistry Heterocyclic Building Blocks Pyridines 3-bromo-2-chloropyridine
Ambeed provide 20 derivatives of 3-bromo-2-chloropyridine.
These compounds have the same murcko framework: 3-bromo-2-chloropyridineSubstitution Reactions: Being a halogenated compound, 3-bromo-2-chloropyridine can undergo substitution reactions. For instance, it can undergo nucleophilic substitution reactions with nucleophiles such as amines or thiols to replace the bromine or chlorine atom.
Cross-Coupling Reactions: It can participate in cross-coupling reactions, such as Suzuki-Miyaura coupling, Stille coupling, or Heck reaction, where the halogen atom serves as a site for bond formation with other organic molecules.
Metalation Reactions: 3-bromo-2-chloropyridine can undergo metalation reactions with strong bases or metal reagents to form organometallic compounds, which can further participate in various organic transformations.
Oxidation or Reduction Reactions: The bromine and chlorine atoms in the molecule can be subjected to oxidation or reduction reactions, leading to the formation of different functional groups.
Heterocyclic Chemistry: It can participate in various heterocyclic chemistry reactions, such as forming fused heterocycles or undergoing ring-opening reactions.
Functional Group Transformations: The functional groups present in 3-bromo-2-chloropyridine can undergo transformations such as halogenation, oxidation, reduction, or substitution to yield diverse organic compounds.
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3-Bromo-2-chloro-6-(chloromethyl)pyridine
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5-Bromo-6-chloro-N-methylpyridine-3-sulfonamide
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3-Bromo-2-chloro-5-(trifluoromethoxy)pyridine
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3-Bromo-2-chloro-6-(difluoromethyl)pyridine
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3-Bromo-2-chloro-5-(trifluoromethyl)pyridine
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3-Bromo-2-chloro-4-(difluoromethoxy)pyridine
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5-Bromo-6-chloropyridine-3-sulfonyl chloride
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(5-Bromo-6-chloropyridin-2-yl)methanamine hydrochloride