Chemistry Organic Building Blocks Bromides 3-bromo-2-fluorophenol
Ambeed provide 4 derivatives of 3-bromo-2-fluorophenol.
These compounds have the same murcko framework: benzene,and at least 3 kinds of functional groups( —Br,—F,—OH).
Grignard Reaction: Bromobenzene can react with a Grignard reagent (organomagnesium compound) to form a new carbon-carbon bond, leading to the introduction of various functional groups.
Fluorine Substitution: Fluorobenzene can undergo further substitution reactions to replace the fluorine atom with other functional groups. This can be achieved through nucleophilic aromatic substitution reactions. The electron-withdrawing nature of fluorine can affect the regioselectivity and reactivity of such substitutions.
Hydroxylation: Phenol can be hydroxylated using various oxidizing agents to introduce additional hydroxyl groups onto the ring.
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