Chemistry Organic Building Blocks Bromides methyl 3-bromo-4-fluorobenzoate
These compounds have the same murcko framework: benzene,and at least 3 kinds of functional groups( —Br,—F,—COOCH3).
Electrophilic Aromatic Substitution (EAS): Bromobenzene can react with electrophiles in substitution reactions, such as nitration, sulfonation, halogenation, and Friedel-Crafts acylation/alkylation.
Metalation Reactions: Fluorobenzene can undergo metalation reactions, where a metal species (such as an organolithium or organomagnesium compound) replaces a hydrogen atom on the benzene ring. These metalated intermediates can then be used in various synthetic transformations.
Reduction: Methyl benzoate can be reduced to benzyl alcohol using reducing agents like lithium aluminum hydride (LiAlH4) or sodium borohydride (NaBH4). The ester functional group is reduced to an alcohol functional group.
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Methyl 5-bromo-2-chloro-4-fluorobenzoate
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Methyl 5-bromo-4-fluoro-2-methoxybenzoate
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Methyl 2-amino-5-bromo-4-fluorobenzoate