Chemistry Heterocyclic Building Blocks Pyridines 3-bromopyridin-2-ol
Substitution reactions: The bromine atom can undergo substitution reactions, where it can be replaced by other nucleophiles. This can include nucleophilic substitution reactions such as SN1 or SN2 reactions.
Hydroxylation reactions: The hydroxyl group can undergo reactions typical of alcohols, including esterification, etherification, oxidation, and dehydration reactions.
Nucleophilic addition reactions: The hydroxyl group can act as a nucleophile and undergo addition reactions with electrophiles.
Metal-mediated reactions: The bromine atom can participate in reactions involving metals, such as palladium-catalyzed cross-coupling reactions or Grignard reactions.
Oxidation reactions: The molecule can undergo oxidation reactions, either at the hydroxyl group or at the pyridine ring.
Reduction reactions: Conversely, the molecule can also undergo reduction reactions, where either the bromine atom or the hydroxyl group can be reduced.
Acid-base reactions: The hydroxyl group can act as a weak acid, undergoing deprotonation in the presence of strong bases.
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