Chemistry Heterocyclic Building Blocks Pyridines 3-chloro-2-methoxypyridine
Ambeed provide 16 derivatives of 3-chloro-2-methoxypyridine.
These compounds have the same murcko framework: 3-chloro-2-methoxypyridineNucleophilic Substitution: The chlorine atom can undergo nucleophilic substitution reactions with nucleophiles such as amines or thiols, leading to the displacement of the chlorine atom by the nucleophile.
Electrophilic Aromatic Substitution: The pyridine ring can undergo electrophilic aromatic substitution reactions, where an electrophile replaces a hydrogen atom on the ring. For instance, the methoxy group can be replaced by an electrophile under suitable conditions.
Reductive Reactions: The compound may undergo reduction reactions, where functional groups are reduced to different oxidation states. For example, the chlorine atom could be reduced to a chloride anion.
Oxidation Reactions: Conversely, the compound could undergo oxidation reactions, where functional groups are oxidized to different oxidation states. For example, the methyl group could be oxidized to a carboxylic acid or an aldehyde.
Ring Transformation Reactions: The pyridine ring can undergo ring transformation reactions under specific conditions, leading to the formation of different cyclic structures.
Condensation Reactions: The compound may participate in condensation reactions with suitable reagents, leading to the formation of new carbon-carbon or carbon-heteroatom bonds.
Alkylation/Acylation Reactions: The pyridine ring can undergo alkylation or acylation reactions, where alkyl or acyl groups are introduced onto the ring.
Framework+−
By Key Group+−
By Parent Nucleus+−
By Functional Group+−
Formula Weight+−
Deals click to sign in and save
3-Chloro-2-methoxy-5-methylpyridine
click to sign in and save
3-Chloro-2-methoxypyridine-5-boronic acid
click to sign in and save
3-Chloro-4-hydroxymethyl-2-methoxypyridine
click to sign in and save
(3-Chloro-2-methoxypyridin-4-yl)boronic acid
click to sign in and save
3-Chloro-2-methoxy-5-(trifluoromethyl)pyridine
click to sign in and save
3-Chloro-2-methoxy-4-(trifluoromethyl)pyridine
Deals click to sign in and save
Methyl 5-chloro-6-methoxynicotinate
click to sign in and save
(5-Chloro-6-methoxypyridin-2-yl)methanamine