Chemistry Heterocyclic Building Blocks Pyridines 3-ethoxypyridine
Ambeed provide 12 derivatives of 3-ethoxypyridine.
These compounds have the same murcko framework: 3-ethoxypyridineNucleophilic Substitution: The ethoxy group can act as a nucleophile, undergoing substitution reactions with electrophiles. For instance, it can react with alkyl halides to form alkylated products.
Acylation: The pyridine ring can undergo acylation reactions, where an acyl group is introduced onto the ring. This could occur through reactions with acyl chlorides or acid anhydrides to form amides or esters.
Oxidation: The pyridine ring can be oxidized under certain conditions to form various oxidation products. For example, oxidation with strong oxidizing agents like chromic acid could lead to the formation of pyridine N-oxides.
Reduction: Reduction reactions can modify the functional groups present. For instance, reduction of the nitro group (if present) can lead to the formation of the corresponding amine.
Heterocyclic Chemistry: Being a heterocyclic compound, 3-ethoxypyridine can participate in various heterocyclic chemistry reactions such as cycloadditions, ring-opening reactions, etc.
Metal Complexation: pyridine derivatives often form stable complexes with various metal ions. Coordination chemistry with transition metals can result in the formation of metal complexes with altered reactivity and properties.
Condensation Reactions: 3-Ethoxypyridine can undergo condensation reactions with carbonyl compounds to form α,β-unsaturated compounds or with amines to form imines.
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