Chemistry Heterocyclic Building Blocks Pyridines 3-hydrazineylpyridine
Ambeed provide 8 derivatives of 3-hydrazineylpyridine.
These compounds have the same murcko framework: 3-hydrazineylpyridineAcylation: 3-hydrazinylpyridine can undergo acylation reactions where an acyl group (-CO-R) is introduced onto the nitrogen atom of the hydrazine moiety or onto the nitrogen atom of the pyridine ring.
Alkylation and Arylation: The hydrazine nitrogen and the nitrogen of the pyridine ring can both undergo alkylation or arylation reactions, where an alkyl or aryl group replaces a hydrogen atom on these nitrogen atoms.
Substitution Reactions: 3-hydrazinylpyridine can undergo nucleophilic substitution reactions at the nitrogen atoms or at the positions on the pyridine ring.
Condensation Reactions: It can participate in condensation reactions with carbonyl compounds or other electrophiles to form hydrazones or other derivatives.
Oxidation and Reduction Reactions: The hydrazine group can be oxidized to form nitrogen gas or reduced to form secondary amines or hydrazines of different oxidation states.
Coordination Chemistry: Due to the presence of both nitrogen and oxygen atoms in the structure, 3-hydrazinylpyridine can act as a ligand in coordination chemistry, forming complexes with metal ions.
Ring-closure Reactions: Depending on the reaction conditions and functional groups present, 3-hydrazinylpyridine may participate in ring-closure reactions to form heterocyclic compounds.
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5-Hydrazinyl-2-methoxypyridine dihydrochloride
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5-Hydrazinyl-2-methoxypyridine hydrochloride
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3-Bromo-5-hydrazineylpyridine dihydrochloride
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1-(6-Methylpyridin-3-yl)hydrazine hydrochloride