Chemistry Organic Building Blocks Iodides 1-bromo-3-iodobenzene
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —I,—Br).
Electrophilic Aromatic Substitution (EAS): Iodobenzene can undergo typical electrophilic aromatic substitution reactions, similar to benzene. The presence of the iodine atom makes the ring more reactive toward electrophiles due to its electron-donating inductive effect. Common EAS reactions include nitration, halogenation, sulfonation, and Friedel-Crafts reactions.
Suzuki-Miyaura Coupling: Bromobenzene can participate in cross-coupling reactions with organoboron compounds in the presence of a palladium catalyst, resulting in the formation of biaryl compounds.
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Methyl 3-iodoimidazo[1,2-a]pyridine-6-carboxylate
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1-Bromo-3-iodo-5-(trifluoromethoxy)benzene