Chemistry Heterocyclic Building Blocks Pyridines 3-methylpyridin-2-amine
Ambeed provide 7 derivatives of 3-methylpyridin-2-amine.
These compounds have the same murcko framework: 3-methylpyridin-2-amineubstitution Reactions: The amino group can undergo substitution reactions with electrophiles. For example, it can react with alkyl halides to form N-alkylated products.
Acylation: The amino group can undergo acylation reactions with acyl chlorides or acid anhydrides to form amides.
Protonation: The amino group can be protonated under acidic conditions to form a positively charged ammonium ion.
Deamination: Under certain conditions, the amino group can be removed from the molecule, resulting in deamination.
Condensation Reactions: The amino group can participate in condensation reactions, such as the formation of imines or Schiff bases with carbonyl compounds.
Oxidation: The methyl group or the amino group can undergo oxidation reactions under suitable conditions.
Reduction: The pyridine ring can be reduced to piperidine under certain conditions.
Metal Complex Formation: The amine nitrogen can coordinate with transition metals to form metal complexes.
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4-Chloro-3-methylpyridin-2-amine