Chemistry Heterocyclic Building Blocks Pyrazoles 4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine
Ambeed provide 14 derivatives of 4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine.
These compounds have the same murcko framework: 4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine.
Arylation or Alkylation: If there are suitable positions on the pyrazolo[3,4-c]pyridine ring, it can undergo arylation or alkylation reactions with electrophilic aromatic compounds or alkylating agents.
Oxidation: Depending on the conditions, pyrazolo[3,4-c]pyridine may be susceptible to oxidation reactions, leading to the formation of various oxidized products.
Substitution Reactions: The pyrazolo[3,4-c]pyridine ring can undergo substitution reactions with nucleophiles if there are suitable leaving groups or electrophilic sites.
Reduction: Under appropriate conditions, pyrazolo[3,4-c]pyridine can be reduced to its corresponding dihydro or tetrahydro derivative.
Heterocycle Formation: Pyrazolo[3,4-c]pyridine can participate in heterocycle formation reactions, either as a reactant or by forming new rings through intramolecular reactions.
Functional Group Transformations: If there are functional groups attached to the molecule, they may undergo various transformations, such as hydrolysis, esterification, or amidation, depending on the reaction conditions and reagents used.
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tert-Butyl 3-methyl-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate
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5-(tert-Butoxycarbonyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxylic acid
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tert-Butyl 3-hydroxy-1,4,6,7-tetrahydropyrazolo[4,3-c]pyridine-5-carboxylate
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5-Boc-3-iodo-4,5,6,7-tetrahydropyrazolo[4,3-c]pyridine
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4,5,6,7-Tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-amine dihydrochloride
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3-(Trifluoromethyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine dihydrochloride
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tert-Butyl 6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate
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4,5,6,7-Tetrahydro-1H-pyrazolo[4,3-c]pyridine dihydrochloride
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tert-Butyl 3-bromo-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate
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tert-Butyl 3-(hydroxymethyl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate
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tert-Butyl 3-amino-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate
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tert-Butyl 3-(trifluoromethyl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate
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tert-Butyl 3-(aminomethyl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate
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Ethyl 4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxylate hydrochloride