Chemistry
Heterocyclic Building Blocks
Pyridines
4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine
Substitution Reactions: Depending on the functional groups present, substitution reactions can occur. For example, if there is a halogen substituent (e.g., chloro, bromo) on the ring, it can undergo nucleophilic substitution reactions with nucleophiles such as amines, hydroxide ions, or other nucleophiles.
Alkylation: The pyridine nitrogen can also be alkylated with alkyl halides or other alkylating agents.
Oxidation: The thiazole ring can be oxidized under appropriate conditions. For instance, it can be oxidized to form a thiazole-4-carboxylic acid or other oxidized products.
Reduction: The thiazole ring can be reduced to its saturated form, a tetrahydrothiazole, using reducing agents like hydrogen and a catalyst or other reducing agents.
Ring Opening: Under certain conditions, the ring system may undergo ring-opening reactions, forming open-chain compounds. The specific conditions and products would depend on the reagents used.
Condensation Reactions: It can participate in condensation reactions with other compounds, especially those containing carbonyl groups, to form products like Schiff bases or other adducts.
Heterocycle Synthesis: It can be used as a starting material in the synthesis of various heterocyclic compounds through different reactions like cyclization, annulation, or rearrangement reactions.
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tert-Butyl 2-amino-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate
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2-Bromo-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine
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5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-amine
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Ethyl 5-Boc-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylate
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5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride
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Ethyl 4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylate hydrochloride
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tert-Butyl 2-bromo-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate
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4,5,6,7-Tetrahydro-2-methylthiazolo[5,4-c]pyridine
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5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine
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4,5,6,7-Tetrahydro-thiazolo[5,4-c]pyridin-2-ylamine