Chemistry Heterocyclic Building Blocks Pyridines 4,5,6,7-tetrahydrothieno[3,2-c]pyridine
Ambeed provide 9 derivatives of 4,5,6,7-tetrahydrothieno[3,2-c]pyridine.
These compounds have the same murcko framework: 4,5,6,7-tetrahydrothieno[3,2-c]pyridine.
Reduction: The double bonds within the thieno ring can be reduced to saturated bonds using reducing agents like hydrogen and a catalyst, or using specific reducing agents like lithium aluminum hydride (LiAlH4) or sodium borohydride (NaBH4).
Oxidation: The sulfur atom in the thieno ring can be oxidized to sulfoxides or sulfones using appropriate oxidizing agents.
Substitution Reactions: The hydrogen atoms on the thieno ring or the pyridine ring can be replaced with other functional groups through substitution reactions.
Condensation Reactions: The compound may undergo condensation reactions with appropriate reagents to form larger molecules.
Grignard Reactions: If there are suitable functional groups, the compound can react with a Grignard reagent to form various products.
Heterocyclization Reactions: The compound itself can act as a nucleophile or electrophile in heterocyclization reactions.
Metalation Reactions: Depending on the conditions, the compound may form complexes with various metals, leading to new reactivity.
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tert-Butyl 6,7-dihydrothieno[3,2-c]pyridine-5(4H)-carboxylate
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Methyl 4,5,6,7-tetrahydrothieno[3,2-c]pyridine-2-carboxylate hydrochloride
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5-(tert-Butoxycarbonyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine-2-carboxylic acid
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tert-Butyl 2-bromo-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-carboxylate
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4-Methyl-4H,5H,6H,7H-thieno[3,2-c]pyridine
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4,5,6,7-Tetrahydrothieno[3,2-c]pyridine hydrochloride
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4,5,6,7-Tetrahydrothieno[3,2-c]pyridine-2-carboxylic acid hydrochloride
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tert-Butyl 3-bromo-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-carboxylate