4-(3-phenoxypropyl)morpholine-Morpholines| Ambeed

Chemistry Heterocyclic Building Blocks Morpholines 4-(3-phenoxypropyl)morpholine

4-(3-phenoxypropyl)morpholine

Ambeed provide 7 derivatives of 4-(3-phenoxypropyl)morpholine.

These compounds have the same murcko framework: 4-(3-phenoxypropyl)morpholine.

Acid-Catalyzed Hydrolysis: 4-(3-phenoxypropyl)morpholine can undergo hydrolysis in the presence of strong acids, such as concentrated sulfuric acid or hydrochloric acid. This reaction would result in the cleavage of the morpholine ring, leading to the formation of 3-phenoxypropanol and morpholine as products.
Alkylation: The phenoxypropyl side chain contains a reactive alkyl halide-like group, which can undergo alkylation reactions with nucleophiles. For example, it can react with strong nucleophiles like sodium hydroxide (NaOH) to form sodium 4-(3-phenoxypropyl)morpholine, which can then be further modified.
Oxidation: The phenoxypropyl side chain may be susceptible to oxidation reactions under certain conditions, resulting in the formation of various oxidation products.
Reduction: The compound can undergo reduction reactions in the presence of reducing agents, leading to the reduction of functional groups within the molecule.
Etherification: Depending on the reaction conditions and reagents, the phenoxypropyl group may undergo etherification reactions, leading to the formation of ether derivatives.
Grignard Reactions: The compound may react with Grignard reagents to form new compounds through nucleophilic addition reactions.
Amination: 4-(3-phenoxypropyl)morpholine can undergo amination reactions to introduce amino groups into the molecule, depending on the specific reagents and conditions.