Chemistry Heterocyclic Building Blocks Pyrimidines 4-(trifluoromethyl)pyrimidin-2-amine
Ambeed provide 6 derivatives of 4-(trifluoromethyl)pyrimidin-2-amine.
These compounds have the same murcko framework: pyrimidine
Amination reactions: The amine group in the molecule can participate in reactions with various electrophiles, leading to the formation of substituted amines.
Nucleophilic substitution reactions: The nitrogen atom in the pyrimidine ring can act as a nucleophile in substitution reactions with suitable electrophiles.
Condensation reactions: The amine group and the pyrimidine ring may participate in condensation reactions with other functional groups, leading to the formation of larger and more complex molecules.
Metal-catalyzed reactions: The trifluoromethyls group can be involved in reactions catalyzed by transition metals, potentially leading to diverse transformations.
Halogenation reactions: The presence of the trifluoromethyls group and amino group can make the compound susceptible to halogenation reactions under appropriate conditions.
Framework+−
By Key Group+−
By Parent Nucleus+−
By Functional Group+−
Formula Weight+−
Deals click to sign in and save
2-Amino-4-(trifluoromethyl)pyrimidine-5-carbaldehyde
click to sign in and save
5-Bromo-4-(trifluoromethyl)pyrimidin-2-amine
click to sign in and save
4-Methyl-6-(trifluoromethyl)pyrimidin-2-amine
click to sign in and save
2-Amino-4-hydroxy-6-trifluoromethylpyrimidine
click to sign in and save
Ethyl 2-amino-4-(trifluoromethyl)pyrimidine-5-carboxylate