Chemistry Heterocyclic Building Blocks Indoles 4-bromo-1H-indole

4-bromo-1H-indole

Ambeed provide 25 derivatives of 4-bromo-1H-indole.

These compounds have the same murcko framework: indole

Substitution Reactions: The bromine atom can undergo nucleophilic substitution reactions, where a nucleophile replaces the bromine. For example, substitution with a nucleophile such as an amine or an organometallic reagent can occur.
Suzuki-Miyaura Coupling: 4-bromo-1H-indole can participate in Suzuki-Miyaura coupling reactions with boronic acids or boronate esters, leading to the formation of biaryl compounds.
Lithiation: The bromine atom is a good leaving group, making 4-bromo-1H-indole suitable for lithiation reactions. This involves the replacement of the bromine with a lithium atom, generating a reactive intermediate that can be used in further reactions.
Bromination: 4-bromo-1H-indole can participate in bromination reactions, where the bromine atom is replaced by another halogen.
Metal-Catalyzed Reduction: The bromo group can be reduced to form the corresponding indole using metal-catalyzed hydrogenation or other reduction methods.
Arylation Reactions: 4-bromo-1H-indole can undergo palladium-catalyzed arylation reactions, introducing aryl groups at the bromine position.
Amidation: The bromo group can be converted to an amine group through amidation reactions, for example, by reacting with ammonia or amine derivatives.

Further Reading:
Typically In Stock
Purity
  • Please Select
  • 99+%
  • 99%
  • 98+%
  • 98%
  • 97+%
  • 97%
  • 96+%
  • 96%
  • 95+%
  • 95%
  • 93%
  • 90+%
  • 90%
Size
  • Please Select
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 5g
  • 10g
  • 25g
  • 100g
  • 500g
  • 1000g
  • 1kg
Conditions to empty

Framework+−

(1-(tert-butoxycarbonyl)-1H-indol-2-yl)boronic acid (1H-indol-2-yl)boronic acid (1H-indol-2-yl)methanol (3aS,7aS)-octahydro-1H-indole (9H-fluoren-9-yl)methyl (2-(1H-indol-3-yl)ethyl)carbamate 1,2,3,4-tetrahydrocyclopenta[b]indole 1,2-dimethyl-1H-indole 1-(1H-indol-1-yl)ethan-1-one 1-(1H-indol-3-yl)-N,N-dimethylmethanamine 1-(1H-indol-3-yl)ethan-1-one 1-(phenylsulfonyl)-1H-indole 1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine 1-benzyl-1H-indole 1-ethyl-1H-indole 1-methyl-1H-indole 1-methyl-1H-indole-2-carboxylic acid 1-methyl-1H-indole-3-carbaldehyde 1-methyl-1H-pyrrolo[2,3-b]pyridine 1-phenyl-1H-indole 1H-indol-3-ol 1H-indol-3-yl acetate 1H-indol-4-amine 1H-indol-4-ol 1H-indol-5-ol 1H-indol-6-amine 1H-indol-6-ol 1H-indol-7-amine 1H-indole-2-carbaldehyde 1H-indole-2-carbonitrile 1H-indole-3-carbaldehyde 1H-indole-3-carbonitrile 1H-indole-3-carboxylic acid 1H-indole-4-carboxylic acid 1H-indole-5-carbonitrile 1H-indole-5-carboxylic acid 1H-indole-6-carbonitrile 1H-indole-6-carboxylic acid 1H-indole-7-carbonitrile 1H-indole-7-carboxylic acid 1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde 1H-pyrrolo[2,3-b]pyridine-5-carbaldehyde 2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole 2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole 2,3-dimethyl-1H-indole 2-(1,3,2-dioxaborolan-2-yl)-1-methyl-1H-indole 2-(1H-indol-1-yl)acetic acid 2-(1H-indol-3-yl)acetic acid 2-(1H-indol-3-yl)ethan-1-amine 2-(1H-indol-3-yl)ethan-1-ol 2-(2-methyl-1H-indol-3-yl)acetic acid 2-(4-fluorophenyl)-1H-indole 2-methyl-1H-indole-3-carbaldehyde 2-methyl-1H-pyrrolo[2,3-b]pyridine 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione 3-(1H-indol-3-yl)propanoic acid 3-(piperidin-4-yl)-1H-indole 3-iodo-1H-pyrrolo[2,3-b]pyridine 3-methyl-1H-indole 3H-indole 4-bromo-1H-indole 4-chloro-1H-indole 4-fluoro-1H-indole 4-fluoro-1H-pyrrolo[2,3-b]pyridine 4-fluoroindoline-2,3-dione 4-methoxy-1H-indole 4-methyl-1H-indole 4-nitro-1H-indole 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole 5-(benzyloxy)-1H-indole 5-bromo-1-methyl-1H-indole 5-chloro-1H-indole 5-chloro-1H-indole-2-carboxylic acid 5-chloro-1H-pyrrolo[2,3-b]pyridine 5-fluoro-1H-indole 5-fluoro-1H-pyrrolo[2,3-b]pyridine 5-fluoroindolin-2-one 5-methoxy-1H-indole 5-methoxy-2-methyl-1H-indole 5-methyl-1H-indole 5-nitro-1H-indole 6-(trifluoromethyl)-1H-indole 6-bromo-1-methyl-1H-indole 6-bromo-1H-indole 6-bromo-1H-pyrrolo[2,3-b]pyridine 6-chloro-1H-indole 6-chloro-1H-pyrrolo[2,3-b]pyridine 6-fluoro-1H-indole 6-methoxy-1H-indole 6-methyl-1H-indole 6-methyl-1H-pyrrolo[2,3-b]pyridine 6-nitro-1H-indole 7-bromo-1H-indole 7-bromoindoline-2,3-dione 7-chloro-1H-indole 7-fluoro-1H-indole 7-fluoro-1H-indole-2-carboxylic acid 7-methoxy-1H-indole 7-methyl-1H-indole 7-nitro-1H-indole 9H-pyrido[3,4-b]indole benzo[cd]indol-2(1H)-one ethyl 1H-indole-3-carboxylate ethyl 5-chloro-1H-indole-2-carboxylate ethyl 5-fluoro-1H-indole-2-carboxylate ethyl 6-chloro-1H-indole-2-carboxylate ethyl 7-chloro-1H-indole-2-carboxylate methyl 1H-indole-3-carboxylate methyl 1H-indole-4-carboxylate methyl 1H-indole-5-carboxylate methyl 1H-indole-6-carboxylate methyl 1H-indole-7-carboxylate methyl 2-(1H-indol-3-yl)acetate N-(2-(1H-indol-3-yl)ethyl)acetamide spiro[indoline-3,4'-piperidin]-2-one tert-butyl 1H-indole-1-carboxylate tert-butyl 1H-pyrrolo[2,3-b]pyridine-1-carboxylate tert-butyl 2-(1,3,2-dioxaborolan-2-yl)-1H-indole-1-carboxylate tert-butyl 3-(hydroxymethyl)-1H-indole-1-carboxylate tert-butyl 3-bromo-1H-indole-1-carboxylate tert-butyl 3-iodo-1H-indole-1-carboxylate tert-butyl 5-methoxy-1H-indole-1-carboxylate tryptophan

By Key Group+−

aminoindole azaindole benzoindole benzyloxyindole biindolinylidene boronate-indole bromo-indole-carboxylate bromo-indole-carboxylic acid bromo-methyl-indole bromoindole chlorindole-carboxylic acid chloro-indole-carboxylate chloro-methyl indole chloroindole cyanoindole dihydroindolo dimethyl-indole dioxaborolan-indole dioxaborolan-indole-carboxylate fluorindole-carboxylic acid fluoro-indole-carboxylate fluoroindole fluoromethyl-indole formyl-indole-carboxylate formylindole hydroxyindole hydroxyisoindoline hydroxymethy-indole-carboxylate indol-amine indol-methanamine indol-methanol indol-one indole-boronic acid/ester indole-carbonitrile indole-ethanol indole-ethylamine indole-hydrochloride indole-hydroxyl indolecarboxylate indolecarboxylic iodo-indole isoindole methanoisoindole methoxy-indole-carboxylate methoxy-methyl-indole methoxyindole methyl-indole-carboxylic-acid methyl-nitro-indole methylindole nitro-indole-carboxylate nitroindole phenyl-indole piperidine-indole pyridinoindole pyrimido-indole trifluoromethyl-indole

By Parent Nucleus+−

Aromatic Heterocycles Benzofurans Indolines Other Aromatic Heterocycles Piperazines Piperidines Pyrazoles Pyridines Pyrimidines Pyrroles Pyrrolidines Pyrrolines

By Functional Group+−

Alcohols Aldehydes Alkenyls Amides Amines Aryls Bromides Carboxylic Acid Salts Carboxylic Acids Chiral Building Blocks Chlorides Esters Ethers Fluorinated Building Blocks Hydrazides Hydrazines Hydroxylamines Iodides Ketones Nitriles Nitroes Organoboron Phenols Sulfamides Sulfides Trifluoromethyls

By Chemical Elements+−

    Bx
    Cx
    Nx
    Ox
    Fx
    Six
    Px
    Sx
    Clx
    Brx
    Ix

    Formula Weight+−

    cLogP+−

    H-Acceptors+−

    H-Donors+−

    Polar Surface Area+−

    Druglikeness+−

    NNCH/NNH+−

    sp3-Atoms+−

    Non-Aromatic Rings+−

    Aromatic Rings+−

    Rotatable Bonds+−

    By Configuration+−

    Similar Frameworks 1H-indol-4-amine 4-fluoro-1H-indole 4-chloro-1H-indole 4-methyl-1H-indole 7-methyl-1H-indole 6-bromo-1H-indole 7-bromo-1H-indole More
    4-Bromo-6-(trifluoromethyl)-1H-indole

    Deals click to sign in and save

    A1012121000342-93-798%

    4-Bromo-6-(trifluoromethyl)-1H-indole

    $28.00/250mg

    Detail
    Methyl 4-bromo-2-methyl-1H-indole-6-carboxylate

    Deals click to sign in and save

    A2488531260383-49-095%

    Methyl 4-bromo-2-methyl-1H-indole-6-carboxylate

    $117.00/250mg

    Detail
    2-(4-Bromo-3-indolyl)acetonitrile

    Deals click to sign in and save

    A26086489245-35-295%

    2-(4-Bromo-3-indolyl)acetonitrile

    $48.00/1g

    Detail
    4-Bromo-1H-indole-6-carboxamide

    click to sign in and save

    A1321763955978-87-798%

    4-Bromo-1H-indole-6-carboxamide

    $816.00/1g

    Detail
    Methyl 4-bromo-1H-indole-6-carboxylate

    click to sign in and save

    A101336882679-96-197%

    Methyl 4-bromo-1H-indole-6-carboxylate

    $14.00/1g

    Detail
    Ethyl 4-bromo-1H-indole-2-carboxylate

    click to sign in and save

    A172228103858-52-295%

    Ethyl 4-bromo-1H-indole-2-carboxylate

    $770.00/25g

    Detail
    4-Bromo-1H-indole-2-carboxylic acid

    click to sign in and save

    A22600516732-64-295%

    4-Bromo-1H-indole-2-carboxylic acid

    $43.00/1g

    Detail
    4-Bromo-1H-indole-6-carboxylic acid

    click to sign in and save

    A651040374633-27-997%

    4-Bromo-1H-indole-6-carboxylic acid

    $79.00/5g

    Detail
    4-Bromoindole

    click to sign in and save

    A11908852488-36-597% HPLC

    4-Bromoindole

    $5.00/1g

    Detail
    4,6-Dibromo-1H-indole

    click to sign in and save

    A29481399910-50-695%

    4,6-Dibromo-1H-indole

    $22.00/100mg

    Detail
    4-Bromoindole-3-carboxyaldehyde

    click to sign in and save

    A19661298600-34-198%

    4-Bromoindole-3-carboxyaldehyde

    $299.00/25g

    Detail
    Methyl 4-bromo-1H-indole-2-carboxylate

    click to sign in and save

    A191445167479-13-298%

    Methyl 4-bromo-1H-indole-2-carboxylate

    $119.00/5g

    Detail
    4-Bromo-6-methoxy-1H-indole

    click to sign in and save

    A171194393553-55-498%

    4-Bromo-6-methoxy-1H-indole

    $183.00/1g

    Detail
    4-Bromo-5-chloro-1H-indole

    click to sign in and save

    A5312311191028-48-497%

    4-Bromo-5-chloro-1H-indole

    $51.00/250mg

    Detail
    4-Bromo-2-methyl-1H-indole

    click to sign in and save

    A2635016127-18-098%

    4-Bromo-2-methyl-1H-indole

    $40.00/250mg

    Detail
    4-Bromo-6-chloro-1H-indole

    click to sign in and save

    A435005885519-23-395%

    4-Bromo-6-chloro-1H-indole

    $15.00/100mg

    Detail
    4-Bromo-5-methoxy-1H-indole

    click to sign in and save

    A15895290858-86-998%

    4-Bromo-5-methoxy-1H-indole

    $107.00/1g

    Detail
    4-Bromo-6-fluoro-1H-indole

    click to sign in and save

    A186894885520-70-795%

    4-Bromo-6-fluoro-1H-indole

    $58.00/1g

    Detail
    4-Bromo-1H-indole-6-carbonitrile

    click to sign in and save

    A867830374633-29-197%

    4-Bromo-1H-indole-6-carbonitrile

    $1136.00/5g

    Detail
    4-Bromo-6-nitro-1H-indole

    click to sign in and save

    A168194885520-47-895%

    4-Bromo-6-nitro-1H-indole

    $336.00/1g

    Detail
    4-Bromo-5-fluoro-1H-indole

    click to sign in and save

    A1204001227493-96-095%

    4-Bromo-5-fluoro-1H-indole

    $40.00/100mg

    Detail
    4-Bromo-5-methyl-1H-indole

    click to sign in and save

    A243942610794-15-598%

    4-Bromo-5-methyl-1H-indole

    $98.00/250mg

    Detail
    4-Bromo-6-methyl-1H-indole

    click to sign in and save

    A105925885520-48-998%

    4-Bromo-6-methyl-1H-indole

    $30.00/100mg

    Detail
    4-Bromo-1H-indol-6-amine

    click to sign in and save

    A587710375369-03-297%

    4-Bromo-1H-indol-6-amine

    $147.00/1g

    Detail
    4-Bromo-1H-indol-7-ol

    click to sign in and save

    A7425241167056-91-897%

    4-Bromo-1H-indol-7-ol

    $531.00/1g

    Detail
    1    page 1 of 1 Pages

    Inquiry