Chemistry Organic Building Blocks Iodides 4-chloro-2-iodoaniline
These compounds have the same murcko framework: benzene,and at least 3 kinds of functional groups( —I,—NH2,—Cl).
Cross-Coupling Reactions: Iodobenzene is commonly used in cross-coupling reactions, such as Suzuki-Miyaura, Negishi, and Stille reactions. These reactions involve coupling an aryl halide (like iodobenzene) with an organometallic reagent, leading to the formation of new carbon-carbon bonds.
Schiff Base Formation: Aniline can react with 【aldehydes|https://www.ambeed.com/aldehydes.html】 and 【ketones|https://www.ambeed.com/ketones.html】 to form Schiff bases, which are important intermediates in organic synthesis.
Sandmeyer Reaction: Chlorobenzene can be converted to other aryl halides through the Sandmeyer reaction, involving replacement of the chlorine atom with other halogens.
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