Chemistry Heterocyclic Building Blocks Pyridines 4-ethoxypyridine
Ambeed provide 7 derivatives of 4-ethoxypyridine.
These compounds have the same murcko framework: 4-ethoxypyridineNucleophilic Substitution: The ethoxy group (-OCH2CH3) can act as a nucleophile, participating in substitution reactions with electrophiles. For instance, it can undergo substitution reactions with alkyl halides or other electrophiles at the pyridine ring.
Acylation: The pyridine nitrogen atom can undergo acylation reactions with acyl halides or acid anhydrides to form amides.
Alkylation: The pyridine nitrogen can also undergo alkylation reactions with alkyl halides or alkyl sulfonates to form N-alkyl pyridinium salts.
Reduction: The pyridine ring can undergo reduction reactions under appropriate conditions, converting the nitrogen atom to a saturated amine.
Oxidation: The ethoxy group or the pyridine ring can undergo oxidation reactions, depending on reaction conditions and reagents used.
Esterification: The pyridine nitrogen can react with carboxylic acids to form pyridinium carboxylates.
Catalytic Reactions: It can participate in various catalytic reactions involving transition metals or organometallic complexes.
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1-(4-Ethoxypyridin-3-yl)butan-1-one