Chemistry Heterocyclic Building Blocks Pyridines 4-isopropyl-2-(pyridin-2-yl)-4,5-dihydrooxazole
Ambeed provide 16 derivatives of 4-isopropyl-2-(pyridin-2-yl)-4,5-dihydrooxazole.
These compounds have the same murcko framework: 4-isopropyl-2-(pyridin-2-yl)-4,5-dihydrooxazoleElectrophilic Aromatic Substitution: The pyridine ring in the compound contains a nucleophilic nitrogen atom. It can undergo electrophilic aromatic substitution reactions with electrophiles like acyl chlorides, sulfonyl chlorides, and other electrophilic reagents.
Nucleophilic Substitution: The oxazole ring contains a nucleophilic oxygen atom. It can react with electrophiles or undergo nucleophilic substitution reactions. For example, it can be acylated with acyl chlorides, alkylated with alkyl halides, or reacted with various electrophiles.
Base-Catalyzed Reactions: The compound may undergo reactions with strong bases, such as deprotonation of acidic protons, leading to the formation of new compounds.
Redox Reactions: Depending on the specific functional groups present, it might undergo redox reactions with oxidizing or reducing agents.
Hydrolysis: If the compound contains ester or amide functional groups, it can undergo hydrolysis reactions under acidic or basic conditions.
Cyclization Reactions: The compound contains a heterocyclic ring (oxazole), which can participate in various cyclization reactions with appropriate reagents.
Metal-Catalyzed Reactions: Transition metal catalysts can facilitate various reactions involving this compound, including cross-coupling reactions, hydrogenation, and more.
Framework+−
By Key Group+−
By Parent Nucleus+−
By Functional Group+−
Formula Weight+−
click to sign in and save
2-[(4R)-4,5-Dihydro-4-(1-methylethyl)-2-oxazolyl]pyridine
click to sign in and save
(R)-2-(5-Fluoropyridin-2-yl)-4-isopropyl-4,5-dihydrooxazole
click to sign in and save
(S)-4-Isopropyl-2-(4-methoxy-6-methylpyridin-2-yl)-4,5-dihydrooxazole
click to sign in and save
(R)-2-(5-Chloropyridin-2-yl)-4-isopropyl-4,5-dihydrooxazole
click to sign in and save
(S)-4-Isopropyl-2-(5-(trifluoromethyl)pyridin-2-yl)-4,5-dihydrooxazole
click to sign in and save
(R)-4-Isopropyl-2-(5-(trifluoromethyl)pyridin-2-yl)-4,5-dihydrooxazole
click to sign in and save
(R)-4-Isopropyl-2-(4-(trifluoromethyl)pyridin-2-yl)-4,5-dihydrooxazole
click to sign in and save
(R)-2-(5-Bromopyridin-2-yl)-4-isopropyl-4,5-dihydrooxazole
click to sign in and save
(S)-4-Isopropyl-2-(6-methylpyridin-2-yl)-4,5-dihydrooxazole
click to sign in and save
(S)-4-Isopropyl-2-(4-(trifluoromethyl)pyridin-2-yl)-4,5-dihydrooxazole
click to sign in and save
(S)-2-(5-Bromopyridin-2-yl)-4-isopropyl-4,5-dihydrooxazole
click to sign in and save
(R)-4-Isopropyl-2-(6-methylpyridin-2-yl)-4,5-dihydrooxazole
click to sign in and save
(S)-2-(5-Chloropyridin-2-yl)-4-isopropyl-4,5-dihydrooxazole
click to sign in and save
(S)-4-Isopropyl-2-(pyridin-2-yl)-4,5-dihydrooxazole
click to sign in and save
(R)-4-Isopropyl-2-(4-methoxy-6-methylpyridin-2-yl)-4,5-dihydrooxazole
click to sign in and save
(S)-2-(5-Fluoropyridin-2-yl)-4-isopropyl-4,5-dihydrooxazole