Chemistry Heterocyclic Building Blocks Thiazoles 5,6-dihydrobenzo[d]thiazol-7(4H)-one
Ambeed provide 5 derivatives of 5,6-dihydrobenzo[d]thiazol-7(4H)-one.
These compounds have the same murcko framework: 5,6-dihydrobenzo[d]thiazol-7(4H)-one.
Alkylation or Arylation: If there are suitable reaction sites, you can alkylate or arylate the compound using alkyl or aryl halides in the presence of a base or other suitable conditions.
Reduction: You can reduce the carbonyl group (C=O) to the corresponding alcohol (C-OH) using reducing agents like sodium borohydride (NaBH4) or lithium aluminum hydride (LiAlH4).
Oxidation: Depending on the conditions and reagents, you may be able to oxidize the compound to form various products.
Ring Opening: If conditions are appropriate, the thiazole ring can undergo ring-opening reactions to form different products.
Substitution Reactions: If there are suitable leaving groups, you can carry out substitution reactions like nucleophilic substitution.
Cyclization: In some cases, the compound may participate in intramolecular cyclization reactions, leading to the formation of cyclic compounds.
Hydrolysis: The compound may undergo hydrolysis of the carbonyl group, resulting in the formation of a carboxylic acid or an alcohol, depending on the reaction conditions.
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2-Amino-5,5-dimethyl-5,6-dihydrobenzo[d]thiazol-7(4H)-one
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2-Bromo-5,6-dihydrobenzo[d]thiazol-7(4H)-one
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2-Amino-5,6-dihydrobenzo[d]thiazol-7(4H)-one
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2-Amino-6-(propylamino)-5,6-dihydrobenzo[d]thiazol-7(4H)-one hydrochloride