Chemistry Heterocyclic Building Blocks Thiophenes 5-benzyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
Ambeed provide 7 derivatives of 5-benzyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridine.
These compounds have the same murcko framework: 5-benzyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridine.
Aromatic Substitution: The benzyl group in the molecule can undergo various aromatic substitution reactions, such as electrophilic aromatic substitution, where the benzyl ring may be attacked by electrophiles like bromine or nitration reagents to introduce substituents on the benzyl group.
Ring Opening Reactions: Depending on the reaction conditions, the thieno[3,2-c]pyridine ring may undergo ring-opening reactions. For example, it might react with strong bases or nucleophiles to open the ring and form different products.
Oxidation: The compound may undergo oxidation reactions, especially if it contains easily oxidizable functional groups. Common oxidizing agents like potassium permanganate or chromic acid can be used for such reactions.
Reduction: It may also undergo reduction reactions if exposed to reducing agents like sodium borohydride or lithium aluminum hydride. This can lead to the reduction of various functional groups in the molecule.
Alkylation/Acylation: The compound can be alkylated or acylated to introduce alkyl or acyl groups at suitable positions, depending on the reaction conditions and choice of reagents.
Substitution Reactions: Substituents on the molecule may undergo substitution reactions. For example, the benzyl group may be substituted with other groups or replaced by a hydrogen atom.
Heterocyclic Chemistry: The presence of the thieno[3,2-c]pyridine ring suggests that it may participate in various heterocyclic chemistry reactions, such as cyclization reactions or reactions with other heterocyclic compounds.
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