Chemistry Heterocyclic Building Blocks Pyridines 5-bromo-2-iodopyridine
Ambeed provide 5 derivatives of 5-bromo-2-iodopyridine.
These compounds have the same murcko framework: 5-bromo-2-iodopyridineSubstitution Reactions: The bromine and iodine atoms are both susceptible to substitution reactions, where they can be replaced by other nucleophiles. For example, they can undergo nucleophilic aromatic substitution reactions with suitable nucleophiles.
Cross-Coupling Reactions: The compound can participate in transition-metal-catalyzed cross-coupling reactions. For instance, it could undergo Suzuki coupling with boronic acids or Stille coupling with stannanes, where the bromine or iodine atom acts as a leaving group.
Redox Reactions: The compound can participate in various redox reactions involving its halogen substituents. For instance, it can undergo oxidative addition or reductive elimination reactions in the presence of suitable reagents or catalysts.
Functional Group Transformations: The bromine and iodine atoms can be further functionalized through various transformations. For example, they can be converted to other functional groups such as amines, alcohols, or carboxylic acids through appropriate synthetic methods.
Halogenation Reactions: The compound can undergo further halogenation reactions under certain conditions, where additional halogen atoms are introduced onto the pyridine ring.
Ring-Forming Reactions: The compound can participate in ring-forming reactions, leading to the formation of fused or bridged ring systems depending on the reaction conditions and reagents employed.
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