Chemistry Heterocyclic Building Blocks Pyridines 5-bromo-6-chloropyridin-2-amine
Nucleophilic Substitution: The bromide or chloropyridine group can undergo nucleophilic substitution reactions, where the halogen is replaced by a nucleophile, such as amines or other nucleophilic reagents.
Amidation: The amine group can undergo amidation reactions to form amides when reacted with carboxylic acids or acid derivatives.
Reductive Amination: The amine group can undergo reductive amination reactions with carbonyl compounds (aldehydes or ketones) in the presence of reducing agents to form secondary or tertiary amines.
Cross-Coupling Reactions: The compound can participate in cross-coupling reactions such as Suzuki coupling or Heck coupling, where the halogen group acts as a leaving group and couples with another organic substrate in the presence of suitable catalysts.
Substitution Reactions: The compound can undergo substitution reactions with various electrophiles to introduce functional groups at the 2-position of the pyridine ring.
Heterocyclic Chemistry: It can participate in various heterocyclic chemistry reactions due to its pyridine ring, such as cyclization reactions to form fused heterocycles or ring-opening reactions.
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5-Bromo-6-chloro-3-nitropyridin-2-amine