Chemistry Heterocyclic Building Blocks Pyridines 5-chloropyridin-2-ol
Ambeed provide 15 derivatives of 5-chloropyridin-2-ol.
These compounds have the same murcko framework: 5-chloropyridin-2-olSubstitution Reactions: The chlorine atom can undergo substitution reactions with nucleophiles, such as substitution with hydroxide ions to form 5-hydroxypyridin-2-ol.
Esterification: The hydroxyl group can undergo esterification reactions with carboxylic acids or acyl chlorides to form esters.
Oxidation: The hydroxyl group can undergo oxidation reactions to form aldehydes or ketones, depending on the reaction conditions.
Reduction: The chlorine atom or the hydroxyl group can undergo reduction reactions to form different products, such as 5-chloro-2-pyridinamine or 2-pyridinol, respectively.
Metal Complexation: The compound can complex with metal ions due to the presence of both chlorine and hydroxyl functional groups.
Condensation Reactions: The compound can undergo condensation reactions with other molecules containing suitable functional groups, leading to the formation of heterocyclic compounds or polymers.
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Methyl 3,5-dichloro-6-hydroxypicolinate
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5-Chloro-3-(trifluoromethyl)pyridin-2-ol
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5-Chloro-2-hydroxy-6-methylnicotinic acid
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5-Chloro-2-hydroxy-6-methylnicotinonitrile
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3,5-Dichloro-6-hydroxypicolinic acid