Chemistry Heterocyclic Building Blocks Pyridines 6,7-dihydro-5H-cyclopenta[b]pyridine
Ambeed provide 18 derivatives of 6,7-dihydro-5H-cyclopenta[b]pyridine.
These compounds have the same murcko framework: 6,7-dihydro-5H-cyclopenta[b]pyridine.
Aromatic Substitution: Depending on the reaction conditions, the pyridine ring may undergo electrophilic aromatic substitution reactions. For example, it can react with strong electrophiles like nitration or halogenation agents.
Reduction: The dihydropyridine ring can be reduced to form the corresponding piperidine derivative, typically with the use of reducing agents such as hydrogen gas and a metal catalyst.
Oxidation: Oxidation of the compound may lead to the formation of a pyridine or pyridinium derivative.
Ring Opening: The cyclopentane ring can be cleaved under certain conditions, leading to the formation of open-chain compounds. This can occur through reactions like ozonolysis or ring-opening reactions with nucleophiles.
Substitution Reactions: The compound can undergo various substitution reactions at the cyclopentane ring. For example, it can be functionalized with various groups, like alkyl, acyl, or other substituents.
Cycloaddition Reactions: It can participate in cycloaddition reactions with suitable dienophiles, leading to the formation of bridged or fused ring systems.
Retro-Diels-Alder Reaction: If the compound is part of a larger molecule and has been formed through a Diels-Alder reaction, it can undergo a retro-Diels-Alder reaction to revert to the starting materials.
Nucleophilic Addition: Depending on the functional groups present, the compound can undergo nucleophilic addition reactions.
Framework+−
By Key Group+−
By Parent Nucleus+−
By Functional Group+−
Formula Weight+−
Deals click to sign in and save
6,7-Dihydro-5H-cyclopenta[b]pyridin-7-amine hydrochloride
click to sign in and save
4-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridine
click to sign in and save
3-Iodo-6,7-dihydro-5H-cyclopenta[b]pyridine
click to sign in and save
2-Bromo-6,7-dihydro-5H-cyclopenta[b]pyridine
click to sign in and save
6,7-Dihydro-5H-cyclopenta[b]pyridine-3-carboxylic acid
click to sign in and save
6,7-Dihydro-5h-cyclopenta[b]pyridin-7-ol
click to sign in and save
3-Bromo-6,7-dihydro-5H-cyclopenta[b]pyridine
click to sign in and save
(R)-6,7-Dihydro-5H-cyclopenta[b]pyridin-7-amine hydrochloride
click to sign in and save
(R)-6,7-Dihydro-5H-cyclopenta[b]pyridin-7-ol
click to sign in and save
6,7-Dihydro-5H-cyclopenta[b]pyridin-2-amine
click to sign in and save
2-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridine
click to sign in and save
6,7-Dihydro-5H-cyclopenta[b]pyridin-5-ol
click to sign in and save
Ethyl 3-bromo-6,7-dihydro-5H-cyclopenta[b]pyridine-7-carboxylate
click to sign in and save
4-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridin-7-ol
click to sign in and save
(S)-6,7-Dihydro-5H-cyclopenta[b]pyridin-7-ol
Deals click to sign in and save
2,4-Dichloro-6,7-dihydro-5H-cyclopenta[b]pyridine
Deals click to sign in and save
3-Nitro-6,7-dihydro-5H-cyclopenta[b]pyridine