Chemistry Heterocyclic Building Blocks Pyridines 6,7-dihydro-5H-pyrrolo[3,4-b]pyridine
Ambeed provide 5 derivatives of 6,7-dihydro-5H-pyrrolo[3,4-b]pyridine.
These compounds have the same murcko framework: 6,7-dihydro-5H-pyrrolo[3,4-b]pyridine.
Amination: You can perform N-alkylation or N-acylation reactions to introduce various substituents at the nitrogen atom in the pyrrolopyridine ring.
Dehydrogenation: Under certain conditions, you can remove hydrogen atoms from the molecule to create double bonds. For instance, you can use oxidative conditions or catalytic hydrogenation/dehydrogenation.
Cyclization Reactions: Depending on the functional groups present, intramolecular cyclization reactions can be used to form fused ring systems or other heterocyclic compounds.
Halogenation: You can react the compound with halogenating agents like bromine or chlorine to introduce halogen atoms into the molecule.
Substitution Reactions: You can perform substitution reactions at positions that are susceptible to nucleophilic or electrophilic attack, depending on the functional groups present.
Cross-coupling Reactions: Palladium-catalyzed cross-coupling reactions can be used to introduce aryl or alkyl groups at specific positions.
Ring Opening: In some cases, you can perform ring-opening reactions under appropriate conditions to break the ring and form open-chain compounds.
Heterocycle Formation: Depending on the substituents present, you can perform reactions to form other heterocyclic compounds by introducing additional rings or modifying the existing ones.
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3-Bromo-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine hydrochloride
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6,7-Dihydro-5H-pyrrolo[3,4-b]pyridine dihydrochloride
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2-Chloro-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine hydrochloride
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3-(Trifluoromethyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine hydrochloride
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6,7-Dihydro-5H-pyrrolo[3,4-b]pyridine hydrochloride