6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine-Pyrimidines| Ambeed

Chemistry Heterocyclic Building Blocks Pyrimidines 6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine

6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine

Ambeed provide 8 derivatives of 6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine.

These compounds have the same murcko framework: 6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine.

Amination: You can introduce amino groups to the pyrimidine ring by reacting it with various aminating agents, such as ammonia or primary amines. This reaction can lead to the formation of substituted pyrimidines.
Alkylation: Alkylating agents, such as alkyl halides or alkyl sulfonates, can be used to introduce alkyl groups onto the pyrimidine ring. This reaction can lead to the synthesis of substituted pyrimidines.
Nucleophilic Substitution: The pyrimidine ring can undergo nucleophilic substitution reactions at positions with suitable leaving groups, resulting in the substitution of these groups with various nucleophiles.
Cyclization: Depending on the reaction conditions and reagents used, cyclization reactions can lead to the formation of fused ring systems or other heterocyclic compounds.
Oxidation and Reduction: You can perform oxidation or reduction reactions on the pyrimidine ring to introduce oxygen or hydrogen atoms, respectively, at various positions.
Functional Group Transformations: Various functional group transformations, such as halogenation, nitration, and acylation, can be performed on 6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine to introduce different functional groups.
Condensation Reactions: This compound can participate in condensation reactions with other suitable reactants to form larger, more complex molecules.
Ring-Opening Reactions: Depending on the conditions and reagents, ring-opening reactions of the pyrimidine ring may be possible, leading to the formation of different products.