Chemistry
Heterocyclic Building Blocks
Pyridines
6-bromopyridin-3-ol
Substitution reactions: The bromine atom can undergo substitution reactions with various nucleophiles, such as amines or thiols, leading to the formation of new products.
Oxidation reactions: The alcohol group (-OH) can undergo oxidation to form an aldehyde or a carboxylic acid, depending on the conditions and reagents used.
Esterification: The alcohol group can react with carboxylic acids or acyl chlorides in the presence of an acid catalyst to form esters.
Ether formation: The alcohol group can react with alkyl halides in the presence of a base to form ethers.
Ring-closure reactions: Under appropriate conditions, the compound can undergo ring-closure reactions to form cyclic compounds.
Metal-mediated reactions: The compound can undergo reactions with various metal catalysts to form organometallic compounds or to facilitate other transformations.
Halogenation reactions: The pyridine ring can undergo halogenation reactions under certain conditions, leading to the substitution of hydrogen atoms with halogen atoms.
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