Chemistry Heterocyclic Building Blocks Pyridines 6-chloro-5-iodopyridin-2-amine
Ambeed provide 3 derivatives of 6-chloro-5-iodopyridin-2-amine.
These compounds have the same murcko framework: 6-chloro-5-iodopyridin-2-amineSubstitution Reactions: The chlorine and iodine atoms can undergo substitution reactions with various nucleophiles or electrophiles, depending on the reaction conditions.
Metalation Reactions: The amino group can coordinate with various transition metals, leading to metalation reactions which can further participate in cross-coupling or other organic transformations.
Reductive Reactions: The iodine atom can undergo reduction to iodide, which can then participate in various reactions such as nucleophilic substitution or addition reactions.
Aromatic Substitution Reactions: The aromatic ring can undergo substitution reactions such as electrophilic aromatic substitution or nucleophilic aromatic substitution, depending on the reaction conditions and the nature of the substituents.
Functional Group Transformations: The amine group can undergo various transformations such as acylation, alkylation, or amidation reactions, leading to the formation of new functional groups.
Cross-Coupling Reactions: The halogen atoms can participate in cross-coupling reactions with suitable partners under appropriate reaction conditions, leading to the formation of biaryl compounds or other coupled products.
Cyclization Reactions: The compound can participate in cyclization reactions under suitable conditions, leading to the formation of heterocycles or fused ring systems.
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6-Chloro-5-iodo-3-nitropyridin-2-amine