Chemistry Organic Building Blocks Aryls benzyltriphenylphosphonium
Ambeed provide 14 derivatives of benzyltriphenylphosphonium.
These compounds have the same murcko framework: benzyltriphenylphosphonium.
Wittig Reaction: Benzyltriphenylphosphonium can participate in the Wittig reaction, where it reacts with aldehydes or ketones to form olefins (alkenes) through the formation of a phosphonium ylide intermediate.
Nucleophilic Addition: In the presence of strong nucleophiles, benzyltriphenylphosphonium can undergo nucleophilic addition reactions. For instance, it can react with organometallic reagents like Grignard reagents to form new carbon-carbon bonds.
Oxidation: Benzyltriphenylphosphonium can be oxidized to form benzaldehyde or benzoic acid under appropriate conditions.
Reduction: Reduction of benzyltriphenylphosphonium can yield benzylamines or other reduced products. This can be achieved using reducing agents like lithium aluminum hydride (LiAlH4).
Reaction with Electrophiles: Benzyltriphenylphosphonium can also react with electrophiles, leading to the addition of the electrophilic species to the benzyl group.
Cross-Coupling Reactions: Benzyltriphenylphosphonium can participate in cross-coupling reactions, such as the Heck reaction or Suzuki-Miyaura coupling, to form biaryl compounds or other coupled products.
Rearrangements: Under certain conditions, rearrangement reactions may occur involving the benzyl group.
Cyclization Reactions: Benzyltriphenylphosphonium can undergo cyclization reactions, leading to the formation of cyclic compounds when suitable reactants are present.
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(4-Fluorobenzyl)triphenylphosphonium chloride
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(2,4-Dichlorobenzyl)triphenylphosphonium chloride
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(2-Chlorobenzyl)triphenylphosphonium chloride
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(2-Nitrobenzyl)triphenylphosphonium bromide
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(4-Bromobenzyl)triphenylphosphonium bromide
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(4-Chlorobenzyl)triphenylphosphonium chloride
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(4-Methylbenzyl)triphenylphosphonium chloride
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(4-Fluorobenzyl)triphenylphosphonium bromide
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(4-(Methoxycarbonyl)benzyl)triphenylphosphonium chloride
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(3-Methoxybenzyl)triphenylphosphonium chloride
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[4-(Methoxycarbonyl)benzyl](triphenyl)phosphonium bromide