Chemistry Heterocyclic Building Blocks Piperidines 4-(azetidin-1-yl)piperidine
Alkylation: The piperidine nitrogen can be alkylated using alkyl halides or alkyl sulfonates to form N-alkylated derivatives.
Amination: The azetidine nitrogen can undergo amination reactions, where it is converted into a new amine derivative. This can be achieved using various amine sources and appropriate reaction conditions.
Ring Opening: The azetidine ring can be opened under specific reaction conditions, leading to the formation of new compounds. This may involve the use of strong acids or bases.
Substitution Reactions: Other substitution reactions can occur at various positions of the molecule, depending on the reagents and reaction conditions.
Reduction: The molecule can be reduced to form a saturated piperidine derivative. This can be achieved using reducing agents such as lithium aluminum hydride (LiAlH4) or hydrogen gas in the presence of a catalyst.
Oxidation: Oxidation reactions can modify the molecule by introducing oxygen-containing functional groups. This can be achieved using various oxidizing agents.
Cyclization: Depending on the reaction conditions and reagents used, the compound may undergo intramolecular cyclization reactions to form cyclic derivatives.
Hydrolysis: The compound can undergo hydrolysis reactions in the presence of acids or bases, leading to the cleavage of certain bonds and the formation of hydrolyzed products.
Framework+−
By Key Group+−
By Parent Nucleus+−
By Functional Group+−
Heterocyclic related+−
Formula Weight+−
click to sign in and save
1-(Piperidin-4-yl)azetidin-3-ol hydrochloride
click to sign in and save
3-Methyl-1-(piperidin-4-yl)azetidin-3-ol hydrochloride
click to sign in and save
cis-4-(Azetidin-1-yl)-3-fluoropiperidine dihydrochloride
click to sign in and save
4-(3-Fluoroazetidin-1-yl)piperidine dihydrochloride
click to sign in and save
tert-Butyl 4-(3,3-difluoroazetidin-1-yl)piperidine-1-carboxylate
click to sign in and save
4-(Azetidin-1-yl)piperidine dihydrochloride