Chemistry Heterocyclic Building Blocks Pyridines dimethyl(pyridin-3-yl)phosphine oxide
Ambeed provide 7 derivatives of dimethyl(pyridin-3-yl)phosphine oxide.
These compounds have the same murcko framework: dimethyl(pyridin-3-yl)phosphine oxideSubstitution Reactions: DMPPO can undergo substitution reactions, where one functional group is replaced by another. For example, it can undergo nucleophilic substitution reactions with electrophiles.
Metal Complex Formation: Being a phosphine derivative, DMPPO can form metal complexes. These complexes often find applications in coordination chemistry and catalysis.
Oxidation Reactions: Phosphine oxides can be oxidized under appropriate conditions to yield phosphine oxides of higher oxidation states or other products.
Reduction Reactions: DMPPO can be reduced to phosphine or other reduced phosphorus compounds under suitable reaction conditions.
Condensation Reactions: It can participate in condensation reactions, such as the formation of phosphine oxide polymers or the synthesis of heterocyclic compounds.
Catalytic Reactions: DMPPO can serve as a ligand in catalytic reactions, facilitating various transformations such as hydrogenation, hydroformylation, and coupling reactions.
Acid-Base Reactions: DMPPO may undergo acid-base reactions, particularly due to the presence of the pyridine ring, which can act as a basic site.
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(2-Aminopyridin-3-yl)dimethylphosphine oxide
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5-(Dimethylphosphoryl)nicotinic acid
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(4-Aminopyridin-3-yl)dimethylphosphine oxide
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Methyl 5-(dimethylphosphoryl)nicotinate
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5-(Dimethylphosphoryl)nicotinonitrile