furo[3,2-b]pyridine-Furans| Ambeed

Chemistry Heterocyclic Building Blocks Furans furo[3,2-b]pyridine

furo[3,2-b]pyridine

Ambeed provide 7 derivatives of furo[3,2-b]pyridine.

These compounds have the same murcko framework: furo[3,2-b]pyridine.

Electrophilic Aromatic Substitution (EAS): Furo[3,2-b]pyridine can undergo EAS reactions, where an electrophile substitutes a hydrogen on the aromatic ring. This is a common reaction for aromatic compounds.
Alkylation/Acylation: Furo[3,2-b]pyridine can undergo alkylation or acylation reactions where an alkyl or acyl group is added to the nitrogen or oxygen atoms, respectively.
Halogenation: The compound can react with halogens (e.g., chlorine, bromine) to introduce halogen atoms onto the aromatic ring.
Substitution at the Furan Ring: Reactions can occur at the furan ring, such as Diels-Alder reactions or nucleophilic additions to the C-2 or C-5 positions of the furan ring.
Metalation: The nitrogen atom in furo[3,2-b]pyridine can coordinate with transition metal ions, allowing for various organometallic reactions.
Cross-Coupling Reactions: Furo[3,2-b]pyridine can participate in various cross-coupling reactions, such as Suzuki-Miyaura, Stille, or Negishi reactions.
Ring Opening Reactions: Depending on the conditions and reagents, furo[3,2-b]pyridine can undergo ring-opening reactions, potentially leading to the formation of more complex structures.