furo[3,2-c]pyridine-Furans| Ambeed

Chemistry Heterocyclic Building Blocks Furans furo[3,2-c]pyridine

furo[3,2-c]pyridine

Ambeed provide 7 derivatives of furo[3,2-c]pyridine.

These compounds have the same murcko framework: furo[3,2-c]pyridine.

Nucleophilic Aromatic Substitution: Depending on the substitution pattern, furo[3,2-c]pyridine can also undergo nucleophilic aromatic substitution reactions. This typically occurs when there are electron-withdrawing groups on the ring that make it more susceptible to nucleophilic attack.
Reduction: Furo[3,2-c]pyridine can be reduced to its corresponding dihydrofuro[3,2-c]pyridine under suitable conditions. Common reducing agents such as hydrogen gas with a catalyst (e.g., palladium on carbon) or metal hydrides (e.g., sodium borohydride) can be used for this purpose.
Oxidation: Furo[3,2-c]pyridine can undergo oxidation reactions, typically at the furan ring. Oxidizing agents like strong acids or peroxides can be used for this purpose.
Grignard Reactions: Furo[3,2-c]pyridine can react with Grignard reagents to form various substituted products through nucleophilic addition reactions.
Cross-Coupling Reactions: Furo[3,2-c]pyridine can participate in cross-coupling reactions with appropriate coupling partners (e.g., aryl or alkyl halides) in the presence of a suitable catalyst (e.g., palladium or nickel catalysts). These reactions can lead to the formation of biaryl compounds.
Ring-opening Reactions: Depending on the reaction conditions and the presence of suitable functional groups, furo[3,2-c]pyridine can undergo ring-opening reactions, leading to the formation of open-chain compounds or other cyclic structures.
Heterocyclic Chemistry: Furo[3,2-c]pyridine can participate in various heterocyclic chemistry reactions, including reactions with other heterocycles or heteroatoms, leading to the formation of complex heterocyclic compounds.