Chemistry Organic Building Blocks Bromides methyl 3-bromo-4-chlorobenzoate
Ambeed provide 4 derivatives of methyl 3-bromo-4-chlorobenzoate.
These compounds have the same murcko framework: benzene,and at least 3 kinds of functional groups( —Br,—Cl,—COOCH3).
Grignard Reaction: Bromobenzene can react with a Grignard reagent (organomagnesium compound) to form a new carbon-carbon bond, leading to the introduction of various functional groups.
Electrophilic Substitution Reactions: Chlorobenzene's electron-rich aromatic ring can undergo substitution reactions where a hydrogen atom is replaced by a chlorine atom. For instance, it can undergo nitration, sulfonation, and Friedel-Crafts alkylation/acylation reactions.
Reduction: Methyl benzoate can be reduced to benzyl alcohol using reducing agents like lithium aluminum hydride (LiAlH4) or sodium borohydride (NaBH4). The ester functional group is reduced to an alcohol functional group.
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Methyl 3-bromo-4-chloro-5-hydroxybenzoate