Chemistry Heterocyclic Building Blocks Pyridines methyl 5-hydroxypicolinate
Ambeed provide 5 derivatives of methyl 5-hydroxypicolinate.
These compounds have the same murcko framework: methyl 5-hydroxypicolinateEsterification: Methyl 5-hydroxypicolinate can react with acids (such as carboxylic acids) to form esters.
Hydrolysis: Under acidic or basic conditions, the ester linkage in methyl 5-hydroxypicolinate can undergo hydrolysis to produce the corresponding alcohol and carboxylic acid.
Oxidation: The hydroxyl group in methyl 5-hydroxypicolinate can be oxidized to a ketone or carboxylic acid under suitable conditions.
Substitution reactions: The aromatic ring in methyl 5-hydroxypicolinate can undergo electrophilic aromatic substitution reactions, where functional groups can be added or substituted on the aromatic ring.
Reduction: The carbonyl group in methyl 5-hydroxypicolinate can be reduced to produce a primary alcohol under appropriate reaction conditions.
Cyclization: Depending on the reaction conditions and the presence of other functional groups, methyl 5-hydroxypicolinate can undergo cyclization reactions to form heterocyclic compounds.
Framework+−
By Key Group+−
By Parent Nucleus+−
By Functional Group+−
Formula Weight+−