Chemistry Heterocyclic Building Blocks Pyridines methyl 6-methoxynicotinate
Ambeed provide 4 derivatives of methyl 6-methoxynicotinate.
These compounds have the same murcko framework: methyl 6-methoxynicotinateEster Hydrolysis: Under acidic or basic conditions, ester hydrolysis can occur, leading to the formation of 6-methoxynicotinic acid and methanol.
Substitution Reactions: The methoxy group (-OCH3) can undergo substitution reactions under appropriate conditions, replacing the methoxy group with another functional group or atom. For example, nucleophilic aromatic substitution reactions may occur.
Oxidation Reactions: The methyl group or the methoxy group may undergo oxidation reactions under certain conditions, leading to the formation of corresponding oxidized products.
Reduction Reactions: Methyl 6-methoxynicotinate can undergo reduction reactions, where functional groups such as carbonyl groups or nitro groups may be reduced to their corresponding alcohol or amine derivatives.
Cyclization Reactions: Depending on the reaction conditions and the presence of appropriate reagents, cyclization reactions may occur, leading to the formation of cyclic compounds.
Cross-Coupling Reactions: Methyl 6-methoxynicotinate can participate in cross-coupling reactions with suitable partners, forming biaryl or heteroaryl compounds.
Acylation Reactions: The carboxylic acid group in methyl 6-methoxynicotinate can undergo acylation reactions with appropriate acylating agents, leading to the formation of esters or amides.
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Methyl 5-amino-6-methoxynicotinate
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Methyl 5-hydroxy-6-methoxynicotinate