Chemistry Heterocyclic Building Blocks Pyridines N,N-dimethylpyridin-2-amine
Ambeed provide 10 derivatives of N,N-dimethylpyridin-2-amine.
These compounds have the same murcko framework: N,N-dimethylpyridin-2-amineAlkylation: The amine group can undergo alkylation reactions, where an alkyl group replaces a hydrogen atom on the nitrogen atom.
Acylation: The amine group can also undergo acylation reactions, where an acyl group (such as an acetyl group) replaces a hydrogen atom on the nitrogen atom.
Nucleophilic substitution: The amine nitrogen can act as a nucleophile in substitution reactions, replacing a leaving group in a suitable electrophilic substrate.
Protonation: The amine nitrogen can be protonated by strong acids to form a positively charged ammonium ion.
Condensation: It can participate in condensation reactions with carbonyl compounds to form imines or Schiff bases.
Oxidation: The amine group can be oxidized to form N-oxide derivatives under appropriate conditions.
Reduction: It can undergo reduction reactions to form secondary or tertiary amines.
Metal complexation: The nitrogen atom can coordinate with transition metals to form complexes.
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4-Bromo-N,N-dimethylpyridin-2-amine
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3-Bromo-N,N-dimethylpyridin-2-amine
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4-Chloro-2-(dimethylamino)nicotinaldehyde
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2-(Dimethylamino)pyridine-4-carboxylic acid hydrochloride
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2-(Dimethylamino)pyridine-3-carboxylic acid hydrochloride
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5-Amino-3-bromo-2-(N,N-dimethylamino)pyridine