Chemistry Heterocyclic Building Blocks Pyridines N-methylpicolinamide
Ambeed provide 10 derivatives of N-methylpicolinamide.
These compounds have the same murcko framework: N-methylpicolinamideNucleophilic Substitution: NMPA can undergo nucleophilic substitution reactions at the nitrogen or carbon atoms, where the N-methyl group or the picolinamide moiety can be replaced by a nucleophile.
Acylation: NMPA can undergo acylation reactions, where an acyl group can be introduced onto the nitrogen atom or onto the picolinamide ring.
Redox Reactions: NMPA can participate in redox reactions, where it can be oxidized or reduced depending on the reaction conditions and the reagents involved.
Coordination Chemistry: Due to the presence of the nitrogen and oxygen atoms in the picolinamide ring, NMPA can act as a ligand in coordination chemistry, forming complexes with transition metal ions.
Hydrolysis: NMPA can undergo hydrolysis reactions under acidic or basic conditions, resulting in the cleavage of the amide bond and the formation of corresponding acids and amines.
Cyclization: NMPA can participate in cyclization reactions, leading to the formation of cyclic compounds through intramolecular reactions.
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4-Chloro-N-methylpicolinamide hydrochloride
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(6-(Methylcarbamoyl)pyridin-3-yl)boronic acid