Chemistry Heterocyclic Building Blocks Pyridines N-methylpyridin-2-amine
Ambeed provide 47 derivatives of N-methylpyridin-2-amine.
These compounds have the same murcko framework: N-methylpyridin-2-amineNucleophilic substitution: The amine group can act as a nucleophile, replacing a leaving group in a substrate through a substitution reaction.
Acylation: The amine group can undergo acylation reactions, where it reacts with acyl halides or acid anhydrides to form amides.
Alkylation: The amine group can be alkylated with alkyl halides or sulfonates, forming N-alkylated products.
Reduction: The nitrogen in the amine group can be reduced to form secondary or tertiary amines, or even amines with a lower oxidation state.
N-oxidation: The nitrogen in the amine group can be oxidized to form N-oxide derivatives under appropriate conditions.
Heterocyclization: The pyridine ring can participate in various heterocyclization reactions, forming fused or non-fused heterocyclic compounds.
Condensation: The amine group can undergo condensation reactions with carbonyl compounds to form imines or enamines.
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N2-Methylpyridine-2,5-diamine hydrochloride
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(2-(Methylamino)pyridin-3-yl)methyl 2-((tert-butoxycarbonyl)(methyl)amino)acetate
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N-Methyl-5-(trifluoromethyl)pyridin-2-amine
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N2-Methylpyridine-2,4-diamine hydrochloride
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5-Bromo-N2-methylpyridine-2,3-diamine
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6-Methoxy-N-methyl-3-nitropyridin-2-amine
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5-(Aminomethyl)-N-methylpyridin-2-amine
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3,5-Difluoro-N-methylpyridin-2-amine
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N2-Methylpyridine-2,5-diamine dihydrochloride
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(2-(Methylamino)pyridin-4-yl)methanol
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N2-Methyl-5-(trifluoromethyl)pyridine-2,3-diamine
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3-Chloro-N-methyl-5-(trifluoromethyl)pyridin-2-amine
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2-(N-Methylamino)-3-hydroxymethylpyridine
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5-Bromo-N,4-dimethyl-3-nitropyridin-2-amine