Chemistry Heterocyclic Building Blocks Pyridines N-methylpyridin-3-amine
Ambeed provide 15 derivatives of N-methylpyridin-3-amine.
These compounds have the same murcko framework: N-methylpyridin-3-amineNucleophilic substitution reactions: N-Methylpyridin-3-amine can substitute various leaving groups in electrophilic substrates, such as alkyl halides or acyl chlorides, to form new C-N bonds.
N-Alkylation reactions: It can react with alkyl halides or sulfonates to form N-alkylated products.
Acylation reactions: N-Methylpyridin-3-amine can undergo acylation reactions with acyl halides or acid anhydrides to form amides.
Mannich reactions: It can participate in Mannich reactions, adding to electrophilic carbonyl compounds in the presence of a suitable amine and formaldehyde or its equivalent.
N-Heterocyclic carbene formation: It can react with electrophiles such as alkyl halides or sulfonyl chlorides to generate N-heterocyclic carbenes, which are important intermediates in organic synthesis.
Metal-catalyzed transformations: N-Methylpyridin-3-amine can serve as a ligand in metal-catalyzed reactions, enabling various transformations such as cross-coupling reactions or C-H activation reactions.
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Methyl 6-methyl-3-(methylamino)picolinate