Chemistry Heterocyclic Building Blocks Pyridines oxazolo[4,5-b]pyridine
Ambeed provide 7 derivatives of oxazolo[4,5-b]pyridine.
These compounds have the same murcko framework: oxazolo[4,5-b]pyridine.
Acylation: The nitrogen atoms can be acylated with acyl halides or anhydrides to introduce acyl groups.
Alkylation: The nitrogen atoms can be alkylated using alkyl halides or other alkylating agents.
Amination: The nitrogen atoms can be further aminated using appropriate reagents, leading to the introduction of more nitrogen-containing functional groups.
Substitution reactions: Depending on the conditions, substitution reactions can occur at various positions on the ring system.
Ring-opening reactions: Under certain conditions, the oxazole ring may undergo ring-opening reactions, leading to potentially complex products.
Cyclization reactions: Depending on the reactants and conditions, oxazolo[4,5-b]pyridine can participate in cyclization reactions, forming other fused or spirocyclic ring systems.
Metal-catalyzed reactions: Transition metal catalysts can facilitate a variety of transformations, such as cross-coupling reactions, which can lead to the formation of C-C bonds.
Photochemical reactions: Depending on the substituents and conditions, oxazolo[4,5-b]pyridine may undergo photochemical reactions leading to the formation of photoproducts.
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2-Chlorooxazolo[4,5-b]pyridine monohydrochloride