Chemistry Heterocyclic Building Blocks Pyridines phenyl(pyridin-3-yl)methanone
Ambeed provide 9 derivatives of phenyl(pyridin-3-yl)methanone.
These compounds have the same murcko framework: phenyl(pyridin-3-yl)methanone.
Nucleophilic Addition to the Carbonyl Group: The ketone functional group (C=O) is susceptible to nucleophilic attack. This can result in the formation of an alcohol or other derivatives, depending on the nucleophile used.
Aromatic Substitution Reactions: The phenyl ring can undergo various types of electrophilic aromatic substitution reactions, such as halogenation, nitration, sulfonation, and Friedel-Crafts reactions.
Basic Reactions: The pyridine nitrogen is basic and can participate in reactions with acids, such as protonation.
Redox Reactions: Depending on the specific conditions and reactants, redox reactions might occur, potentially leading to the formation of different oxidation states of the compound.
Rearrangements: Depending on the reaction conditions, rearrangements of the molecule may occur, especially if there are suitable functional groups.
Metal Complexation: The ketone group can potentially coordinate with metal ions, forming complexes.
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(5-Bromopyridin-3-yl)(phenyl)methanone
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(4,6-Dichloropyridin-3-yl)(4-fluorophenyl)methanone
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(2,6-Difluoropyridin-3-yl)(phenyl)methanone
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(4-Fluoro-3-methylphenyl)(pyridin-3-yl)methanone
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(2-Amino-4-chloropyridin-3-yl)(phenyl)methanone