Chemistry Heterocyclic Building Blocks Piperidines piperidine-2-carboxylic acid
Ambeed provide 26 derivatives of piperidine-2-carboxylic acid.
These compounds have the same murcko framework: piperidine-2-carboxylic acidAcid-Base Reactions: As a carboxylic acid, pipecolic acid can undergo acid-base reactions. In basic conditions, the carboxylic acid group can be deprotonated to form the carboxylate ion.
Esterification: Pipecolic acid can undergo esterification reactions with alcohols in the presence of acid catalysts to form esters.
Amide Formation: Pipecolic acid can react with amines to form amides. This reaction is similar to the formation of peptide bonds in proteins.
Decarboxylation: Under certain conditions, pipecolic acid can undergo decarboxylation to form piperidine, a six-membered nitrogen-containing heterocycle.
Redox Reactions: Pipecolic acid can undergo redox reactions under appropriate conditions, such as oxidation to form pyridine derivatives or reduction to form piperidine derivatives.
Substitution Reactions: Pipecolic acid can undergo substitution reactions at the piperidine nitrogen or carboxylic acid carbon atom with appropriate reagents.
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(R)-1-Methylpiperidine-2-carboxylic acid
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(2R,4R)-4-Methylpiperidine-2-carboxylic acid
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6-Methylpiperidine-2-carboxylic acid
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Piperidine-2-carboxylic acid hydrochloride
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(2R,4R)-4-Hydroxypiperidine-2-carboxylic acid hydrochloride
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(S)-1-Methylpiperidine-2-carboxylic acid
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1-(tert-Butoxycarbonyl)-4-hydroxypiperidine-2-carboxylic acid
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(2S,4R)-4-Hydroxypiperidine-2-carboxylic acid, N-BOC protected
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(S)-4,4-Difluoropiperidine-2-carboxylic acid hydrochloride
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1-(Tert-butoxycarbonyl)-4,4-difluoropiperidine-2-carboxylic acid
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6-Methylpiperidine-2-carboxylic acid hydrochloride
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1-Methylpiperidine-2-carboxylic acid hydrochloride
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(R)-Piperidine-2-carboxylic acid hydrochloride
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(S)-Piperidine-2-carboxylic acid hydrochloride
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(2S,5S)-5-Hydroxypiperidine-2-carboxylic acid
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(S)-1-(tert-Butoxycarbonyl)-4,4-difluoropiperidine-2-carboxylic acid
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(2S,5S)-5-Hydroxypiperidine-2-carboxylic acid hydrochloride
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(R)-1-Methylpiperidine-2-carboxylic acid hydrochloride