Chemistry Heterocyclic Building Blocks Pyridines pyridin-2-ylmethanamine
Ambeed provide 38 derivatives of pyridin-2-ylmethanamine.
These compounds have the same murcko framework: pyridin-2-ylmethanamineSubstitution Reactions: The amino group (-NH2) in pyridin-2-ylmethanamine can undergo substitution reactions, where it can be replaced by other functional groups or atoms. For example, it can undergo nucleophilic substitution reactions with alkyl halides to form N-alkylated derivatives.
Acylation: The amino group can also undergo acylation reactions, where it reacts with acylating agents to form amides. This can lead to the formation of N-substituted amides.
Reductive Amination: Pyridin-2-ylmethanamine can undergo reductive amination reactions, where the amino group reacts with a carbonyl compound (such as an aldehyde or ketone) in the presence of a reducing agent to form secondary or tertiary amines.
Condensation Reactions: The amino group can undergo condensation reactions with carbonyl compounds or other electrophiles to form imines or iminium ions.
Oxidation: The amine group can be oxidized to form corresponding oximes, nitriles, or nitro compounds under appropriate conditions.
Protonation: The pyridine ring can be protonated under acidic conditions, leading to the formation of pyridinium salts.
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(6-Chloropyridin-2-yl)methanamine dihydrochloride
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(6-Methoxypyridin-2-yl)methanamine dihydrochloride
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(6-Fluoropyridin-2-yl)methanamine dihydrochloride
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Ethyl 6-(aminomethyl)nicotinate hydrochloride
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(6-Bromopyridin-2-yl)methanamine hydrochloride
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(3-Methoxypyridin-2-yl)methanamine hydrochloride
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(4-Methoxypyridin-2-yl)methanamine dihydrochloride
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6-(Aminomethyl)pyridin-3-ol hydrochloride
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(3-Bromopyridin-2-yl)methanamine hydrochloride
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Ethyl 2-(aminomethyl)isonicotinate hydrochloride
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Methyl 6-(aminomethyl)nicotinate hydrochloride
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Methyl 2-(aminomethyl)pyridine-4-carboxylate hydrochloride
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(5-Methylpyridin-2-yl)methanamine hydrochloride
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(3-Bromopyridin-2-yl)methanamine dihydrochloride
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Methyl 6-(aminomethyl)picolinate hydrochloride
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(6-(Trifluoromethyl)pyridin-2-yl)methanamine
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(5-(Trifluoromethyl)pyridin-2-yl)methanamine
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(4-(Trifluoromethyl)pyridin-2-yl)methanamine hydrochloride
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6-(Trifluoromethyl)pyridine-2-methylamine hydrochloride
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(5-(Trifluoromethyl)pyridin-2-yl)methanamine hydrochloride
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(4-Methylpyridin-2-yl)methanamine dihydrochloride
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6-(Aminomethyl)picolinic acid dihydrochloride
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6-(Aminomethyl)nicotinonitrile dihydrochloride
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(5-Methoxy-3-methylpyridin-2-yl)methanamine
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(6-Bromopyridin-2-yl)methanamine dihydrochloride