Chemistry Heterocyclic Building Blocks Pyridines pyridin-3-ylboronic acid
Ambeed provide 49 derivatives of pyridin-3-ylboronic acid.
These compounds have the same murcko framework: pyridin-3-ylboronic acidSuzuki-Miyaura Cross-Coupling Reaction: Pyridin-3-ylboronic acid can undergo Suzuki-Miyaura coupling with aryl or vinyl halides in the presence of a palladium catalyst to form biaryl or styrenyl derivatives.
Boronic Acid Condensation Reaction: Pyridin-3-ylboronic acid can react with diols or diamines to form cyclic boronate esters or amides, respectively, in the presence of suitable catalysts.
Boronic Acid Oxidation: Pyridin-3-ylboronic acid can be oxidized to form the corresponding boronic acid derivatives using oxidants such as hydrogen peroxide or meta-chloroperoxybenzoic acid (mCPBA).
Boronic Acid Reduction: Reduction of pyridin-3-ylboronic acid can yield boronic acid pinacol ester using reducing agents like sodium borohydride.
Boronic Acid Halogenation: Pyridin-3-ylboronic acid can be halogenated at the boron center using halogenating agents, resulting in halogenated boronic acid derivatives.
Boronic Acid Esterification: Pyridin-3-ylboronic acid can undergo esterification reactions with alcohols in the presence of suitable acid catalysts to form boronic acid esters.
Boronic Acid Hydrolysis: Hydrolysis of the boronic acid group can occur under acidic or basic conditions, resulting in the formation of the corresponding phenol or alcohol, respectively.
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(5-(Methoxymethyl)pyridin-3-yl)boronic acid
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(5-(Prop-1-yn-1-yl)pyridin-3-yl)boronic acid
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(2-(tert-Butoxy)pyridin-3-yl)boronic acid
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(5-Chloro-2-isopropoxypyridin-3-yl)boronic acid
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(6-(2-Methoxyethoxy)pyridin-3-yl)boronic acid
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(6-Amino-5-methylpyridin-3-yl)boronic acid
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(2-Butoxy-5-chloropyridin-3-yl)boronic acid
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[6-(Dimethylamino)pyridin-3-yl]boronic acid
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(6-Aminopyridin-3-yl)boronic acid hydrochloride
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(6-(Ethylsulfonyl)pyridin-3-yl)boronic acid
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(4-Methoxypyridin-3-yl)boronic acid hydrochloride
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(5-Chloro-6-isobutoxypyridin-3-yl)boronic acid
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(2-Fluoro-6-propoxypyridin-3-yl)boronic acid
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(6-(Isopropylthio)pyridin-3-yl)boronic acid
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(6-((tert-Butoxycarbonyl)(methyl)amino)pyridin-3-yl)boronic acid
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(2-Methylpyridin-3-yl)boronic acid hydrochloride
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(6-(Methoxycarbonyl)pyridin-3-yl)boronic acid
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(6-(Trifluoromethyl)pyridin-3-yl)boronic acid
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(2-(Trifluoromethyl)pyridin-3-yl)boronic acid
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(4-(2-Hydroxypropan-2-yl)pyridin-3-yl)boronic acid