Chemistry Heterocyclic Building Blocks Pyridines pyridine-2,3-diamine
Ambeed provide 5 derivatives of pyridine-2,3-diamine.
These compounds have the same murcko framework: pyridine-2,3-diamineAcylation: The amino groups can undergo acylation reactions, where an acyl group (-COR) is introduced onto one or both of the amino groups. This reaction is often catalyzed by acyl chlorides or acid anhydrides.
Alkylation: The amino groups can undergo alkylation reactions, where an alkyl group (-R) is introduced onto one or both of the amino groups. Alkylation reactions can be carried out using alkyl halides or alkyl sulfonates.
Amination: Pyridine-2,3-diamine can participate in amination reactions, where other functional groups are converted into amino groups in the presence of ammonia or amine sources.
Reductive amination: This reaction involves the conversion of a carbonyl group (such as an aldehyde or ketone) into an amine group using a reducing agent like sodium cyanoborohydride or sodium triacetoxyborohydride.
Condensation reactions: Pyridine-2,3-diamine can undergo condensation reactions with carbonyl compounds to form imines or Schiff bases.
Metal complexation: The amino groups of pyridine-2,3-diamine can coordinate with metal ions to form metal complexes. These complexes often exhibit interesting properties and can be used in various applications, including catalysis and coordination chemistry.
Oxidation reactions: Pyridine-2,3-diamine can be oxidized under certain conditions to form various products, including pyridine-2,3-diamine oxides or other oxidized derivatives.
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