Chemistry Heterocyclic Building Blocks Pyridines pyridine-2-sulfonyl chloride
Ambeed provide 9 derivatives of pyridine-2-sulfonyl chloride.
These compounds have the same murcko framework: pyridine-2-sulfonyl chlorideSulfonylation: Pyridine-2-sulfonyl chloride reacts with nucleophiles such as alcohols, amines, and thiols to form sulfonate esters, sulfonamides, and sulfonate ethers, respectively.
Amidation: Reaction with amines yields sulfonamides, where the sulfonyl group replaces a hydrogen atom on the nitrogen atom of the amine.
Esterification: alcohols react with pyridine-2-sulfonyl chloride to form sulfonate esters, where the sulfonyl group replaces the hydroxyl group of the alcohol.
Halogenation: It can undergo halogenation reactions with halogenating agents to introduce halogen atoms onto the pyridine ring.
Acylation: Pyridine-2-sulfonyl chloride can acylate aromatic rings, amines, and alcohols, leading to the formation of acylated products.
Substitution Reactions: Under certain conditions, substitution reactions can occur where the sulfonyl group is substituted with other functional groups.
Cyclization Reactions: In specific conditions and with suitable substrates, cyclization reactions involving the pyridine ring and the sulfonyl chloride group can occur, leading to the formation of cyclic compounds.
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Pyridine-2-sulfonyl chloride hydrochloride
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5-Trifluoromethyl-2-pyridinesulfonyl Chloride