Chemistry Heterocyclic Building Blocks Pyridines thieno[3,2-c]pyridine
Ambeed provide 13 derivatives of thieno[3,2-c]pyridine.
These compounds have the same murcko framework: thieno[3,2-c]pyridine.
Arylation and Alkylation: Thieno[3,2-c]pyridine can undergo electrophilic aromatic substitution reactions, where a hydrogen atom on the aromatic ring is replaced by an aryl or alkyl group. For example, it can undergo Friedel-Crafts reactions.
Nucleophilic Substitution Reactions: Depending on the substituents present, thieno[3,2-c]pyridine can potentially undergo nucleophilic substitution reactions at various positions. For instance, if there are halogen substituents, they can be replaced by nucleophiles.
Oxidation and Reduction Reactions: Thieno[3,2-c]pyridine can be subjected to various oxidation and reduction reactions. For instance, it can be oxidized to form a thieno[3,2-c]pyridine oxide.
Metalation Reactions: Thieno[3,2-c]pyridine can coordinate with transition metal ions to form metal complexes. This can lead to various types of reactivity, including catalytic processes.
Ring Opening Reactions: Depending on the conditions, thieno[3,2-c]pyridine may undergo ring-opening reactions. This could lead to the formation of acyclic compounds.
Functional Group Transformations: Like other heterocyclic compounds, thieno[3,2-c]pyridine can undergo reactions involving its functional groups. For example, if it has a ketone group, it could undergo reactions typical of ketones (e.g., nucleophilic addition).
Cyclization Reactions: Depending on the starting materials and reaction conditions, thieno[3,2-c]pyridine can potentially participate in cyclization reactions to form more complex fused ring systems.
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Methyl 3-aminothieno[3,2-c]pyridine-2-carboxylate