Chemistry Organic Building Blocks Amidines
Amidines are organic compounds that contain the functional group RC(NR)NR2, where the R groups may be identical or distinct. They are imine derivatives of amides (RC(O)NR2). The simplest amidine, known as formamidine, is represented by the formula HC(=NH)NH2.
Amidines exhibit significantly higher basicity compared to amides, making them one of the most potent uncharged/unionized bases.
Amidines are capable of forming complexes with a wide range of transition metals, including all first-row transition metals.
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[1,1'-Biphenyl]-4-carboximidamide hydrochloride
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4-Amino-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide
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1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide hydrochloride
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N-Hydroxy-5-(trifluoromethyl)picolinimidamide
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4-(tert-Butyl)picolinimidamide hydrochloride
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N-Hydroxybenzo[d][1,3]dioxole-5-carboximidamide
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tert-Butyl 4-(2-amino-2-(hydroxyimino)ethyl)piperidine-1-carboxylate
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Methyl 6-carbamimidoylnicotinate hydrochloride
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5-Fluoropyridine-3-carboximidamide hydrochloride