Chemistry Heterocyclic Building Blocks Benzothiazoles
Benzothiazole is an aromatic heterocyclic compound with the chemical formula C7H5NS. It is colorless, slightly viscous liquid. Although the parent compound, benzothiazole is not widely used, many of its derivatives are found in commercial products or in nature.
A benzene ring is fused to a 5-membered 1,3-thiazole ring to form benzothiazoles, with the nine atoms of the fused ring and substituents being coplanar.
Benzothiazole, possessing a multitude of appealing biological activities such as antibacterial, anticonvulsant, anticancer, antifungal, antimitotic, and antitumor properties, is a significant category of pharmaceutical drugs.
Benzothiazole derivatives are widely utilized in industry, particularly as corrosion inhibitors and surface-active chelating agents for mineral processing, which are regarded as their most significant industrial applications. Additionally, certain benzothiazole derivatives exhibit strong effectiveness as insecticides and herbicides, serving as valuable contributions to pest control.
An aromatic heterocyclic compound known as Benzothiazole comprises a fused benzene ring and a five-membered 1,3-thiazole ring. Both the nine atoms of the bicyclic structure and the substituents connected to it are coplanar.
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Methyl 6-bromobenzo[d]thiazole-2-carboxylate
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2-Chloro-6-trifluoromethylbenzothiazole
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Methyl 2-(2-aminobenzo[d]thiazol-6-yl)acetate
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2-Methyl-3-propylbenzo[d]thiazol-3-ium iodide
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2-Bromo-6-(trifluoromethoxy)benzo[d]thiazole
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(S)-Benzo[d]thiazol-2-ylmethyl 2-(2-fluorophenylsulfonamido)propanoate